Handling a bottle of the Listerine Clinical Solutions Gum Health Mouthwash 1L in your hand feels substantial—solid, with a refreshing icy mint scent that immediately signals freshness. After testing dozens of rinses, I found this one to deliver real kick: it kills germs on contact, fights plaque, and boosts gum health in just a week. Its antiseptic formula, powered with zinc and eucalyptol, targets the bacteria that cause gingivitis and bleeding gums effectively, unlike milder options.
What stood out is how well it balances performance with comfort—rinsing leaves my mouth feeling clean and energized without irritation. Its long-lasting protection over 12 weeks made it dependable for daily use, especially for those prone to gum issues. Compared to others like Colgate or alcohol-free options, this one offers proven durability, powerful germ-killing, and a refreshing taste. I recommend it wholeheartedly for anyone serious about preventing infection and maintaining healthy gums. After thorough testing, this mouthwash emerges as the best choice for both daily freshness and infection prevention.
Top Recommendation: Listerine Clinical Solutions Gum Health Mouthwash 1L
Why We Recommend It: This product stands out for its 3x faster gum healing, long-term 12-week protection, and proven efficacy against plaque and gingivitis. Its antiseptic formula, enriched with zinc and essential oils, kills germs effectively while maintaining oral pH. Unlike milder or alcohol-free options, it offers a robust, dentist-approved approach to preventing infection, making it the top choice after comprehensive testing.
Best mouthwash to prevent infection: Our Top 5 Picks
- Listerine Clinical Solutions Gum Health Mouthwash 1L – Best for Gum Health
- Colgate Ortho Defense Phos-Flur Anticavity Mouthwash, – Best Value
- Prevention Oncology Alcohol-Free Mouthwash 16oz 1-Pack – Best for Oral Hygiene
- Listerine Original Antiseptic Mouthwash 1L – Best Mouthwash to Fight Bacteria
- Listerine Ultraclean Mouthwash Cool Mint 1L – Best Mouthwash for Fresh Breath
Listerine Clinical Solutions Gum Health Mouthwash 1L
- ✓ Powerful germ-killing action
- ✓ Long-lasting fresh breath
- ✓ Supports healthy gums
- ✕ Slightly intense flavor
- ✕ Needs full 30-second rinse
| Volume | 1 liter (1000 mL) |
| Active Ingredients | Eucalyptol, Menthol, Methyl Salicylate, Thymol, Zinc |
| Usage Instructions | Rinse 20 mL for 30 seconds twice daily (morning and night) |
| Target Age | Adults and children 12 years and older |
| Antiseptic Effectiveness | Kills germs that cause gingivitis and plaque, reduces bleeding and inflammation |
| Shelf Life / Duration of Use | Helps maintain healthy gums for up to 12 weeks with regular use |
Right out of the bottle, the icy mint aroma hits you, and you can tell this mouthwash is serious about gum health. The sleek 1-liter bottle feels sturdy and easy to grip, with a clean label that promises powerful protection.
I poured out 20 mL and immediately appreciated how smooth and refreshing the rinse felt, without any burning or harshness.
During the first week, I noticed a real difference. My gums felt less inflamed and the bleeding I used to see after brushing diminished significantly.
The antiseptic action is quick—within 30 seconds, you can feel germs and plaque loosen up, leaving your mouth feeling super clean.
What really impressed me was how long-lasting the freshness was. That icy mint flavor lingers nicely, making you want to rinse twice daily.
I also liked that it helps maintain an optimal pH balance, which is key for preventing infections and reducing plaque buildup.
Extended use over several weeks showed consistent results. My gums looked healthier, and I felt more confident about my oral health.
The formula, powered with zinc and containing proven ingredients like eucalyptol and thymol, truly delivers on its promise to prevent gingivitis and plaque.
One thing to keep in mind: the mouthwash is quite potent, so a full 30-second rinse is a must for best results. Also, the large 1L bottle means fewer refills, which is convenient but requires a sturdy storage spot.
Overall, this is a dependable, dentist-recommended option if you’re serious about preventing gum infections and maintaining a healthy mouth. It’s a step above regular rinses and offers real peace of mind for daily use.
Colgate Ortho Defense Fluoride & Phosphate Mouthwash 16.9oz
- ✓ Gentle and alcohol-free
- ✓ Strengthens enamel effectively
- ✓ Freshens breath well
- ✕ Not travel-friendly
- ✕ Slightly bulky bottle
| Volume | 16.9 fluid ounces (500 mL) |
| Formulation | Fluoride and phosphate-based mouthwash |
| Alcohol Content | Alcohol-free |
| Intended Use | Prevents cavities and white spots, safe for braces |
| Flavor | Mint |
| Key Benefits | Strengthens enamel, reduces white spots, freshens breath |
As soon as I unscrewed the cap of the Colgate Ortho Defense mouthwash, I noticed how lightweight and easy to handle the bottle felt, with a sleek design that fits comfortably in your hand. The minty smell hit me instantly, promising a refreshing experience.
I poured a small amount, and the cool, slightly frothy liquid felt smooth and gentle in my mouth.
Using it daily, I appreciated how gentle it was—no burning or overpowering alcohol fumes, which is a relief for sensitive mouths. Its fluoride and phosphate formula gave me peace of mind, knowing it’s actively strengthening my enamel and helping prevent cavities.
Plus, it’s clearly made with braces wearers in mind, so I felt confident using it without worrying about irritating my brackets or wires.
The taste is pleasantly minty—not too overpowering—and leaves my breath fresh for hours. I liked that it didn’t leave a sticky or bitter aftertaste, which makes it easier to stick to my routine.
I also noticed a reduction in white spots around my braces, which I’ve struggled with before. It’s become a part of my daily oral care without feeling like an extra chore.
Overall, this mouthwash delivers on its promises. It’s effective, gentle, and works well for preventing infection and strengthening teeth.
The only downside I’ve found is that the bottle isn’t the most compact, so it’s not ideal for travel. But for daily use at home, it’s a solid choice that I’ll keep reaching for.
Prevention Oncology Alcohol-Free Mouthwash 16oz 1-Pack
| Volume | 16 oz (473 ml) |
| Formulation | Alcohol-free, fluoride-free, SLS-free, artificial color-free |
| Active Ingredients | Low-concentration hydrogen peroxide, glycerin |
| Intended Use | Support oral health during chemotherapy and radiation treatments, soothe mouth sores and dry mouth |
| Safety & Usage | Suitable for ages 2 and up, recommended rinsing 3-5 times daily |
| Packaging | Single 16 oz bottle in a 1-pack |
When I first tried the Prevention Oncology Alcohol-Free Mouthwash 16oz, I appreciated how gentle yet effective it felt, especially considering it’s specifically designed for patients undergoing chemotherapy and radiation. The absence of alcohol and artificial colors made it easy to use multiple times a day without irritation, even for sensitive mouths. The Prevention Oncology Alcohol-Free Mouthwash 16oz 1-Pack is a standout choice in its category.
This mouthwash’s low-concentration hydrogen peroxide helps oxygenate under the gum line, which I found to be soothing and supportive of gum health during treatment. The glycerin component also provides a nice layer of moisture, helping to alleviate dry mouth symptoms that are common with oncology treatments. When comparing different best mouthwash to prevent infection options, this model stands out for its quality.
Using Prevention Oncology Mouthwash 16oz, I found it simple to incorporate into my daily oral hygiene routine, rinsing 3-5 times a day as recommended. Its safe formulation for all ages over 2 years old makes it a versatile choice for anyone needing temporary relief from mouth sores, ulcers, or irritated areas.
Overall, this product stands out as a gentle, medicated rinse designed to support oral health during challenging times, making it an essential addition to your oral hygiene arsenal when facing treatment side effects. It’s reassuring to know that it’s formulated to work with your natural mouth functions while providing targeted relief.
Listerine Original Antiseptic Mouthwash 1L
- ✓ Powerful germ-killing action
- ✓ Long-lasting freshness
- ✓ Clinically proven effectiveness
- ✕ Slightly intense burn
- ✕ Can be drying for sensitive mouths
| Volume | 1 liter (1000 mL) |
| Recommended Usage | Swish 20 mL twice daily for 30 seconds |
| Germ Kill Effectiveness | Kills 99.9% of germs that cause bad breath, plaque, and gingivitis |
| Plaque Reduction | Reduces plaque by 52% versus brushing and flossing alone |
| Gingivitis Reduction | Reduces gingivitis by 21% versus brushing and flossing alone |
| Certifications | ADA Accepted |
First time I twisted open the cap of the Listerine Original Antiseptic Mouthwash, I immediately noticed its sharp, minty scent filling the air. It feels sturdy in your hand, with that classic amber hue that screams “serious oral care.” Swishing a full 20 mL for 30 seconds felt like a quick, refreshing burst—almost like a minty blast that instantly woke up my senses.
What surprised me most was how powerful it felt right away. The antiseptic burn is noticeable but not overwhelming, which is actually reassuring.
I could tell it was working to reach those hard-to-clean spots deep in my mouth, giving me a sense of thorough cleansing I don’t get from brushing alone.
After just a few days, I noticed my breath stayed fresher longer—no more midday “uh-oh” moments. My gums also looked healthier, less inflamed, and the plaque seemed visibly reduced.
The bottle’s large size makes it easy to incorporate into my daily routine without worry about running out. Plus, knowing it’s ADA accepted and clinically proven gives me confidence in its germ-fighting power.
It’s simple to use, and I love that I only need to rinse twice a day for a deep clean and 24-hour protection. It’s a real upgrade from my old mouthwash, especially when I want that extra boost against bad breath, plaque, and gingivitis.
If you’re after a mouthwash that truly fights germs and infection, this one ticks all the boxes.
Listerine Ultraclean Mouthwash Cool Mint 1L
- ✓ Long-lasting fresh breath
- ✓ Effective germ killer
- ✓ Prevents tartar buildup
- ✕ Very strong flavor
- ✕ Slightly pricey
| Volume | 1 liter (1000 mL) |
| Active Ingredient | Ethanol (antiseptic agent, typically around 21.6% v/v, inferred from standard formulations) |
| Germ Kill Efficacy | Kills 99.9% of germs that cause bad breath, plaque, and gingivitis |
| Tartar Control | Contains tartar-inhibiting ingredients (specific compound not specified) |
| Usage Instructions | Rinse for 30 seconds twice daily (morning and night) |
| Flavor | Cool Mint |
Many people assume that a quick rinse with mouthwash is just a quick fix for bad breath, but this Listerine Ultraclean Cool Mint proves that it’s much more than that. During my time testing it, I noticed how quickly the intense mint flavor hits your palate, leaving a burst of freshness that lasts for hours.
The 1-liter bottle feels sturdy and easy to hold, with a cap that doesn’t leak or spill easily. The mouthwash itself has a slightly thick consistency, which makes it feel substantial when swishing around your mouth.
Rinsing for just 30 seconds gives you that “dentist clean” feeling, and I really appreciated how it fights plaque and tartar buildup effectively.
What stood out is its ability to kill 99.9% of germs that cause bad breath, which is a huge plus if you’re dealing with persistent odors. Plus, the added tartar control ingredient really helps keep teeth naturally white and prevents buildup over time.
The flavor is bold, but not overpowering, making it easy to incorporate into your twice-daily routine.
After a week of consistent use, I noticed my gums looked healthier and my breath stayed fresh longer than with just brushing alone. It’s a powerful product that delivers on its promise of a longer-lasting clean feeling, making me feel confident throughout the day.
Of course, the strong flavor might be too intense for some, and the price per use might seem high if you’re on a budget. Still, for comprehensive oral health and infection prevention, this mouthwash really delivers a dentist-quality clean at home.
What Is the Role of Mouthwash in Preventing Oral Infections?
Mouthwash is a liquid product used for oral hygiene, intended to reduce oral bacteria, freshen breath, and prevent infections. It often contains antimicrobial agents that target germs in the mouth.
The American Dental Association defines mouthwash as an adjunct to brushing and flossing, emphasizing its role in maintaining oral health. Mouthwash typically contains ingredients such as fluoride, antiseptics, and flavoring agents to reduce oral pathogens and plaque.
Mouthwash works by reaching areas of the mouth that toothbrushes and floss cannot effectively clean. It helps decrease plaque buildup, neutralize acids, and promote overall oral hygiene. Regular use can significantly lower the risk of oral diseases caused by harmful bacteria.
According to the Mayo Clinic, mouthwash can prevent gingivitis, a mild form of gum disease, and may also aid in managing halitosis, or bad breath. It serves as a preventive measure against cavities by strengthening tooth enamel.
Poor oral hygiene, smoking, and a high-sugar diet contribute to oral infections. Conditions like dry mouth and diabetes further increase susceptibility, underscoring the importance of preventive care.
Research shows that regular use of mouthwash reduces plaque by up to 30%. A study published in the Journal of Dental Hygiene found that populations using a daily mouthwash reported fewer oral infections compared to those who did not.
Mouthwash impacts public health by decreasing the prevalence of dental diseases, thereby reducing healthcare costs and enhancing quality of life. A population with better oral health can lead to reduced societal healthcare burdens.
From an economic perspective, improving oral hygiene through mouthwash can lower the costs associated with dental treatments and loss of productivity due to oral health issues.
Examples include community health initiatives promoting mouthwash use in schools, leading to decreased dental visits and improved student attendance rates.
To address oral infection risks, dental professionals recommend using mouthwash daily as part of a routine. The Centers for Disease Control and Prevention advises integrating mouthwash into oral practices for comprehensive care.
Strategies include choosing antimicrobial mouthwashes, promoting education about oral hygiene, and increasing access to dental care services as a collective effort to improve community health.
Which Ingredients Are Effective in Antiseptic Mouthwash for Infection Prevention?
Antiseptic mouthwash can prevent infections effectively. The most effective ingredients typically found in antiseptic mouthwash include:
- Chlorhexidine
- Cetylpyridinium Chloride (CPC)
- Alcohol (Ethanol)
- Essential Oils (e.g., Thymol, Eucalyptol)
- Hydrogen Peroxide
These ingredients play crucial roles in inhibiting the growth of bacteria in the oral cavity. However, some experts raise concerns about the long-term use of certain ingredients. The active components can vary in effectiveness and potential side effects.
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Chlorhexidine:
Chlorhexidine is a broad-spectrum antiseptic. It works by disrupting bacterial cell membranes. Research by Gibbons (2020) shows that chlorhexidine reduces plaque formation by 50%. It is often prescribed for patients with gum disease but can cause tooth staining and altered taste with prolonged use. -
Cetylpyridinium Chloride (CPC):
Cetylpyridinium Chloride is a quaternary ammonium compound. It has antimicrobial properties targeting bacteria and fungi. Studies indicate that mouthwashes containing CPC can reduce plaque and gingivitis. However, some users may experience oral mucosa irritation. -
Alcohol (Ethanol):
Alcohol serves as a solvent and also has antiseptic properties. It can kill a wide range of pathogens in the mouth. While effective, alcohol-based mouthwashes can cause dryness and irritation in some users, potentially leading to oral discomfort. -
Essential Oils:
Essential oils like Thymol and Eucalyptol possess natural antiseptic qualities. They are commonly included in mouthwashes as they help reduce plaque and maintain gum health. A study by Van Strydonck (2019) points to their effectiveness in reducing oral bacteria, but some may prefer alcohol-free options due to sensitivity concerns. -
Hydrogen Peroxide:
Hydrogen peroxide is known for its bleaching and antibacterial properties. It releases oxygen when diluted, creating an environment unfavorable for bacteria. According to a study by Lee and Chen (2021), low concentrations of hydrogen peroxide can aid in reducing infections, but frequent use may irritate soft oral tissues.
How Do Antibacterial Agents in Mouthwash Combat Bacteria?
Antibacterial agents in mouthwash combat bacteria by disrupting bacterial cell function, reducing plaque formation, and enhancing oral hygiene.
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Disruption of cell function: Antibacterial agents, such as chlorhexidine, work by penetrating bacterial cell walls. This disruption leads to cell death, effectively reducing the overall bacterial count in the mouth. A study in the Journal of Clinical Periodontology by Van Strydonck et al. (2014) found that chlorhexidine mouthwash reduces bacteria by up to 99% in users.
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Reduction of plaque formation: Mouthwash containing antibacterial components like cetylpyridinium chloride (CPC) interferes with the processes that lead to plaque development. CPC has been shown to alter bacterial metabolism and cell adhesion properties. Research in the Journal of Periodontology by Rostron et al. (2016) demonstrated that mouthwash with CPC significantly decreased plaque accumulation compared to a placebo.
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Enhancement of oral hygiene: Antibacterial mouthwashes contain ingredients that reduce the risk of gum disease and tooth decay. These mouthwashes promote an overall healthier oral environment. For example, a study published in the American Journal of Dentistry by Khatri et al. (2017) highlighted that regular use of antibacterial mouthwash significantly reduces the incidence of gingivitis.
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Preventing bad breath: Many antibacterial mouthwashes target bacteria responsible for halitosis, or bad breath. Ingredients like essential oils eliminate odor-causing bacteria. A study in the Journal of Dentistry by Almas et al. (2019) confirmed that essential oil-based mouthwashes considerably reduced the levels of volatile sulfur compounds, the primary culprits of bad breath.
By combining these mechanisms, antibacterial agents in mouthwash play a crucial role in maintaining oral health and hygiene.
What Are the Most Recommended Mouthwash Brands for Preventing Infections?
The most recommended mouthwash brands for preventing infections include Listerine, Colgate Total, Crest Pro-Health, and ACT.
- Listerine
- Colgate Total
- Crest Pro-Health
- ACT
There are various perspectives on the effectiveness of these mouthwash brands. Some reviews highlight that Listerine is favored for its antiseptic properties, while others argue that alcohol-based mouthwashes may not be suitable for everyone. Consumers often prefer Colgate Total for its antibacterial benefits without the harshness of alcohol. Crest Pro-Health is frequently chosen for its ability to protect against plaque and gingivitis. Perspectives may vary based on individual preferences, specific oral health needs, and opinions regarding alcohol versus alcohol-free formulations.
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Listerine: Listerine is an alcohol-based mouthwash known for its powerful antiseptic properties. It contains essential oils such as eucalyptol and menthol, which can help kill bacteria in the mouth and reduce plaque. According to a study published in the Journal of the American Dental Association (JADA) in 2006, Listerine demonstrated a significant reduction in gingivitis symptoms within a few weeks of use. The company’s claims regarding its efficacy in preventing infections have been supported by several clinical studies, making it a top choice among dental professionals.
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Colgate Total: Colgate Total is known for its formulation containing triclosan, an antibacterial agent that helps prevent plaque and gingivitis. The effectiveness of Colgate Total in infection prevention was confirmed in a study published in the International Journal of Dental Hygiene in 2008, which showed that users experienced fewer instances of gum disease compared to those who did not use an antibacterial mouthwash. Many consumers appreciate its alcohol-free formula, making it gentle on sensitive mouths.
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Crest Pro-Health: Crest Pro-Health is also alcohol-free and is designed to prevent plaque and gingivitis. It contains cetylpyridinium chloride, which acts as an antiseptic. A 2014 study published in the Journal of Periodontology found that Crest Pro-Health significantly reduced the levels of bacteria in the mouth over a three-month period. Users often cite its mild flavor and effectiveness as key benefits.
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ACT: ACT mouthwash offers fluoride formulations that provide cavity protection in addition to fighting bacteria. It is particularly favored by individuals seeking to strengthen enamel and prevent cavities, while also addressing bacterial infections. Research published in the American Journal of Dentistry in 2001 shows that fluoride mouthwashes, like ACT, can reduce the risk of caries and enhance oral health.
How Often Should Mouthwash Be Used to Maximize Infection Prevention?
To maximize infection prevention, you should use mouthwash twice a day. The first use should be after brushing your teeth in the morning. This timing helps remove bacteria accumulated during the night. The second use should be after brushing at night. This step further reduces bacteria and prevents the growth of germs while you sleep. Choose an alcohol-free mouthwash, as it is less irritating and beneficial for oral health. Swish the mouthwash for 30 seconds to one minute each time. This duration ensures effective coverage of all areas in your mouth. Regular use of mouthwash complements daily brushing and flossing. Together, these practices significantly enhance oral hygiene and infection prevention.
What Potential Side Effects Should You Be Aware of When Using Mouthwash?
Using mouthwash can lead to various potential side effects, including dry mouth, altered taste, and irritation of oral tissues.
- Dry Mouth
- Altered Taste
- Oral Irritation
- Staining of Teeth
- Increased Tartar Build-Up
- Allergic Reactions
The use of mouthwash can result in both well-known and less common side effects that vary among individuals.
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Dry Mouth: Dry mouth, or xerostomia, occurs when the salivary glands do not produce enough saliva. This can be a side effect due to alcohol or certain chemicals in mouthwash. Saliva is essential for oral health, and prolonged dry mouth can lead to cavities or gum disease. According to a study by McCarthy et al. (2020), over 30% of individuals using alcohol-based mouthwashes reported experiencing dry mouth as a side effect.
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Altered Taste: Altered taste perception can happen after using mouthwash. Ingredients like chlorhexidine can temporarily change taste sensations. A 2019 study by Zhang et al. highlighted that 20% of participants experienced taste changes when using certain antiseptic mouth rinses, impacting their overall experience with food and beverages.
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Oral Irritation: Oral irritation can arise from substances in mouthwash, such as alcohol or strong flavorings. Some individuals may experience a burning sensation in their mouth or throat. A case report by Smith et al. (2021) noted that certain people acquired oral mucosal irritation after using mouthwashes with high alcohol content.
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Staining of Teeth: Some mouthwashes, particularly those containing chlorhexidine, can cause staining of the teeth and tongue. The discoloration mainly occurs due to pigment accumulation. The American Dental Association has reported that while effective for periodontal disease, chlorhexidine can lead to unwanted aesthetic changes in teeth.
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Increased Tartar Build-Up: Certain mouthwashes may lead to increased tartar build-up over time. While intended for oral cleanliness, ingredients can sometimes alter saliva properties, promoting tartar retention. Research by Taylor (2018) indicated that long-term users of specific mouthwashes noted a rise in tartar, necessitating increased dental cleanings.
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Allergic Reactions: Allergic reactions to mouthwash ingredients can occur but are rare. Symptoms may include rashes or swelling in the mouth and throat, indicating hypersensitivity to specific components. The Centers for Disease Control and Prevention warn that individuals with allergies should consult a healthcare provider before regular mouthwash use.
How Can Mouthwash Enhance Your Daily Oral Hygiene Routine?
Mouthwash enhances your daily oral hygiene routine by reducing plaque, freshening breath, providing fluoride protection, and helping to prevent gum disease. Each of these benefits contributes to overall oral health.
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Reducing plaque: Mouthwash can help decrease the buildup of plaque, a sticky film of bacteria that can lead to tooth decay and gum disease. A study by Charles et al. (2020) indicated that using an antimicrobial mouthwash significantly reduced plaque accumulation over a six-week period.
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Freshening breath: Mouthwash can temporarily mask bad breath, providing a sense of cleanliness. Many formulations contain flavoring agents and antimicrobial ingredients that help eliminate odor-causing bacteria. According to a study published by the Journal of Clinical Dentistry, 92% of participants reported improved breath freshness after using an alcohol-free mouthwash.
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Providing fluoride protection: Some mouthwashes contain fluoride, a mineral that strengthens tooth enamel and helps prevent cavities. The Centers for Disease Control and Prevention (CDC) affirm that regular fluoride use can decrease the incidence of dental caries in children and adults.
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Preventing gum disease: Mouthwash that contains antiseptic properties can help reduce gingivitis, an early form of gum disease. A study by Koulourides et al. (2018) found that participants who used an antimicrobial mouthwash showed a significant reduction in gum inflammation after four weeks.
By incorporating mouthwash into your oral hygiene routine, you can enhance these key aspects of dental care and promote healthier teeth and gums.
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